Insights and recommendations of African stakeholders on biocontrol technologies for malaria control

Gene Drive Research

African Conversations Initiative

African voices shaping health priorities and innovations for Africa

African Conversations on new Technologies
100+

Experts

20+

Countries

Context

Our origins

Despite decades of concerted efforts to control and eliminate malaria, each year, more than 200 million people are infected with the disease and over 600,000 die. Most of these cases and deaths occur in Africa, among the most vulnerable groups. Over the years, significant progress has been made through a range of interventions and innovations, leading to substantial gains in many settings. Yet malaria remains a persistent and evolving threat, with transmission patterns that vary widely across the continent and even within individual countries. This diversity means that no single solution fits all contexts, and countries must make informed, locally grounded decisions about which strategies are most relevant for their specific situations.

African Conversations began in 2020 as an effort to facilitate inclusive dialogue among diverse African stakeholders on malaria and the potential of innovative approaches to its control, with a particular focus on gene drive modified mosquitoes, a promising new strategy under development. Working with experts across Africa, the initiative aims to elevate voices of African stakeholders on priority needs for malaria control and elimination, strengthen awareness and understanding of changing malaria transmission and control dynamics, and explore the opportunities and implications that advances in technology present for the future of disease control in Africa.

Malaria Cases

263M

Estimated malaria cases worldwide in 2023, with most occurring in Africa

Malaria Deaths

597K

Lives lost to malaria in 2023, with children under 5 accounting for about 80% of all deaths in Africa

Our Story

African Voices, Global Impact

African Conversations is a collective of scientists, researchers, managers, and health champions who believe that for new technologies to succeed, every voice must be heard openly and honestly.

We elevate diverse voices from youth to elders, from community leaders to policymakers, all united to create a healthier Africa.

Key Findings
Research Insights

Stakeholder Insights on Gene Drive Technologies

Since 2020, we have conducted in-depth conversations with hudreds of key stakeholders across Africa about malaria, challenges faced in controlling it, and on whether or not - and how gene drives modified mosquties might fit within the ongoing efforts to control and eliminate this disease. Below are some of the insights from stakeholders across Africa:

  • Malaria continues to pose a significant public health threat across Africa, particularly among vulnerable populations.
  • While current malaria control strategies have achieved important gains, they face limitations that may hinder timely and sustainable elimination of the disease.
  • Emerging tools, including gene drive–modified mosquitoes, offer new opportunities to complement existing malaria control efforts.
  • The development and potential use of gene drive–modified mosquitoes must be guided by African needs, capacities, ecological settings, and governance contexts.
  • Active and meaningful involvement of African stakeholders is essential to ensure that research and development of gene drive–modified mosquitoes are ethical, relevant, and aligned with public health p
Impact

Our Purpose

To facilitate inclusive dialogue with key African stakeholders in order to raise awareness of Africa’s health priorities and the potential of new and emerging solutions.

Inform Stakeholders

Provide accurate information about emerging gene drive technologies to key stakeholders across Africa.

Capture Perspectives

Document diverse viewpoints, concerns, and recommendations from African communities and experts.

Guide Development

Inform responsible development and implementation of gene drive technologies for malaria control.

Engagement

Our Research Impact

Our work is making a real difference in the field of gene drive research across Africa

20+

Countries

African nations actively participated in research

100+

Experts

Leading researchers and professionals involved

30+

Dialogues

Structured discussions on benefits and concerns

50+

Recommendations

Actionable insights for responsible development

Watch & Learn

Understanding Gene Drive Technology

Explore our informative videos about gene drive technologies for malaria control.

Ready to Explore Our Resources?

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